Children injected with vitamin K1 are at highest risk

Children injected with vitamin K1 are at highest risk

[Introduction]A few days ago, the State Drug Administration released the 43rd adverse drug reaction information bulletin, reminding attention to the risk of severe allergic reactions caused by vitamin K1 injection.

  From January 1, 2004 to May 31, 2011, the National Adverse Drug Reaction Monitoring Center received 8,146 cases of adverse reactions / incidents related to vitamin K1 injection.

  Vitamin K1 injection is a national essential medicine list variety, which is more common clinically, and is mainly used for the treatment of various bleeding disorders caused by vitamin K deficiency.

In the National Center database, severe allergic reactions are the most prominent adverse reactions of vitamin K1. Of the 8,146 reports of adverse reactions / events of vitamin K1 injection, there were 1,715 cases of drug use in children (21).

05%), 295 cases of severe cases.

  Qu Caihong, a pharmacist at the Third Affiliated Hospital of Sun Yat-sen University, said that in the oral, intramuscular, and intravenous routes, the risk of adverse reactions to intravenous drugs is relatively higher.

The pediatrician of the Provincial Hospital of Traditional Chinese Medicine also said that intravenous injection of vitamin K1 injection requires special attention, and it is usually safer to intramuscularly give the drug to children.

  According to the analysis of data from the National Center for Adverse Drug Reaction Monitoring, some clinically unreasonable medications have caused adverse reactions of vitamin K1 injection. It is recommended that medical personnel should strictly grasp the indications of vitamin K1 injection and use them in strict accordance with the appropriate dosage prescribed by the drug prescription;Reasonably anticipate the path and strictly control the expected speed.

Medical staff should inquire the patient’s allergy history in detail before taking the medicine, and replace those with allergic reactions contained in vitamin K1 and injection, and those with allergies should use it with caution.